2025

Get details on new feature releases, improvements, and fixes across the DNAnexus Platform, related public tools, and public apps in 2025.

DNAnexus publishes release notes by deployment date. Most platform releases are deployed on Tuesdays throughout the year, which provides a predictable cadence for delivering security updates, reliability improvements, and new platform capabilities.

Product Versioning: Release versions are identified by deployment date. For example, a release deployed on June 17, 2025 can be identified as _20250617 in validation and compliance records. This format helps regulated customers identify exact production release versions for compliance.

December 16, 2025

Release for 16-Dec-2025

• Security patching for Docker containers and EC2 instances

• AWS F1 instance type (FPGA) is scheduled for deprecation on 20-Dec-2025

• Minor refactoring of Titan on the user interface and storage limit controls.

December 9, 2025

Release for 09-Dec-2025

• Security patching for Docker containers and EC2 instances (both every week)

• Refactoring of the infrastructure of Titan and Apollo systems

December 2, 2025

Release for 02-Dec-2025

• Security patching for Docker containers

• Infrastructure upgrades

• Projects set as "no download" also have "no preview"

• Apollo: Adding log₂ and log₁₀ transformation support to histograms and boxplots

November 25, 2025

Release for 25-Nov-2025

• Security patching of Docker containers and EC2 instances

• Enhance symlinks with integrity checks

• Apollo: calculate mean and median statistics for histograms of molecular expression and phenotypic data.

November 18, 2025

Release for 18-Nov-2025

• Security patching for Docker containers

• Improvements to jobmanager and cloud manager

• New instance types added

• Apollo: fix for calculating the max/min and bin width for the histogram for molecular expression data.

November 4, 2025

Release for 04-Nov-2025

• Security patching of EC2 instances and Docker containers

• Download Proxy changes - enforcing the 100kb size of data previews and limiting the number of contiguous downloads to 50 per IP address.

• User Interface enhancements on the Cohort Browser, feature manager, org-members page and others

October 7, 2025

Release for 07-Oct-2025

• Security patching of Docker containers and EC2 instances

• Additional anti-malware messaging to users.

September 30, 2025

Release for 30-Sep-2025

• Security patching for Docker containers and EC2 instances

• Updates to the Trusted Research Environment, Data catalog and respective user interfaces.

September 23, 2025

Release for 23-Sep-2025

• Security patching for Docker containers and EC2 instances

• Refactoring of known issues, including symlinks, user interface fixes and archival processes.

• Apollo: Minor updates to the vizserver

September 16, 2025

Release for 16-Sep-2025

• Security patching of Docker containers and EC2 instances

• Updates to the infrastructure, including migration to the latest version of Python

• Apollo: minor updates to data fields returned

September 9, 2025

Release for 09-Sep-2025

• Security patching of Docker containers and EC2 system in the platform infrastructure

• Titan refactoring and efficiency enhancements

• Apollo: Updates to the p-value approximation in the scatterplots

August 26, 2025

Release for 26-Aug-2025

• Security patching of Docker containers

• Added existing functionality to the Oracle Cloud Infrastructure storage and execution planes:

  • DNA_API_OBJ_CREATE_NEW_FILE_OCI

  • DNA_API_DATA_OBJ_UPLOAD_TO_OPEN_FILE_OCI

  • DNA_API_DATA_OBJ_DOWNLOAD_OCI and

  • DNA_API_DATA_OBJ_REMOVE_FILE_OCI

• Efficiency enhancements to job manager, cloud manager, and user interface

August 12, 2025

Release for 12-Aug-2025

• Security patching for Docker containers and EC2 instances

• Bug fixes for applet and workflow management

• Added AWS F2 instances for compute workloads requiring that instance family

• Apollo: no release

August 5, 2025

Release for 05-Aug-2025

• Security patching of Docker containers

• Improved token revocation process

• Release of new GPU types

• Fixes in JobManager, revocation of credentials from extended sessions

• Apollo: no release

July 29, 2025

Release for 29-Jul-2025

• Security patching for Docker containers

• Titan: tuning and efficiency improvements

• Apollo: no release

July 22, 2025

Release for 22-Jul-2025

• Security patching for EC2 and Docker containers

• Fixes for occasional issues with the product list functionality in the UI

• Fix for occasionally not recognizing user IP addresses during authentication

• Apps: update to LocusZoom to version 1.2.4

• Apollo: no release

July 15, 2025

Release for 15-Jul-2025

• Security patching for Docker containers and EC2 instances

• Changes to error messages to provide additional clarity

• Apps: Publish molecular-expression-assay-loader v2.0.0

• Apollo: expansion of enforcement of read-only functionality for vizserver service, including from workers

July 8, 2025

Release for 08-Jul-2025

• Security patching for Docker containers

• Authorization Server upgrades and other infrastructure updates

• NVIDIA driver updates

• Apollo: update scatterplot to accommodate pivot tables

July 1, 2025

Release for 01-Jul-2025

• Security patching for Docker containers

• Expansion of the Cohort Browser to include multi-assay support, somatic data querying and visualization support, and gene expression data querying and visualization support

• Trusted Research Environment offering

• Apollo: updates of JDK 11 and dxspark 3.5.2 packages, fix for the Pearson coefficient in scatterplots

June 17, 2025

Release for 17-Jun-2025

• Security patching of Docker containers

• TRE updates to accommodate application reviews

• Bug fixes in the user interface

• Apps: Updates of REGENIE to v2.1.0, regenie_test_associations to v2.1.0 and regenie_fit_wgr to v2.1.0

• Apollo: Fix statistics output in histogram API and for multi-assay datasets

June 10, 2025

Release for 10-Jun-2025

• Security patching of EC2 instances and Docker containers

• Bug fixes for writable symlinks, user interface, S3 deletions, and handling of unharvested containers

• Updates to TREs for support of multi-port httpsApp-enabled apps or applets

• Updates to support new GPUs (not available in all regions)

• Cohort Browser: updates of the user interface about tables

• Apollo: internal upgrades to latest JDK and spark pages, implementation of expression locks for internal queries used in boxplot, histogram and scatterplot API and updates to the Pearson correlation coefficient in scatterplot API.

June 3, 2025

Release for 03-Jun-2025

• Security patching of Docker containers

• Authorization Server update and dependencies (infrastructure)

• Cloud Manager upgrades (infrastructure)

• Disallows downloading of shared symlinks

• Minor user interface fixes

• Apollo: interactive features (Cohort Browser and CLI for querying Datasets) are offline in the London region.

• Apollo: Security patching of the Snowflake Python connector. Added binning to the Boxplot functionality.

May 20, 2025

Release for 20-May-2025

• Security patching of Docker containers

• Added features for the TRE administrator to describe projects

• Minor UI changes from bug fixes

• Added the timestamp when archiving initiates

• Added the status of projects reported in the data catalog

• Removed AWS London (General) Thrift server

• Apps: updated FastQC to v4.1.0

• Apollo: no release

May 13, 2025

Release for 13-May-2025

• Security patching of Docker containers

• Incorrect responses are mapped to the appropriate standard HTTP 5xx status codes. Fixes 404 responses on private endpoints.

• Migration to the newer user interface

• Apps Update: REGENIE 2.0.3 and PRSice 2 v1.0.6

• Apollo: update histogram API to include statistics output

May 6, 2025

Release for 06-May-2025

• Security patching of EC2 instances and Docker containers

• Refactoring drive shares to support backwards compatibility with earlier versions.

• Continued hardening of NVIDIA drivers

• Efficiency enhancements for the Trusted Research Environments (TRE)

• Apps Update: PRSice 2, LocusZoom 1.2.3, and REGENIE 2.0.3 released

• Apollo: upgrade JDK in Apache Spark and dxspark 3.5.2 packages,

• Apollo upgrades include:

  • Structural Variant and Fusion support in Somatic Variant

  • Add Pearson correlation coefficient output to scatterplot API

  • Fix fusion post-processing in somatic-genomic-range API

  • Update field validation for locus-details API

  • Add support for partitioned expression datasets

  • Fix fusion affected samples in somatic-genomic-range API

  • Cohort filter optimization for expression assay data

  • Detailed information in output of boxplot API

  • Fix counts for lollipop-plot API

  • Add new feature-expression API

  • Use memory optimized VizserverDataset in vizserver

• Apollo fixes for fusion affected samples in somatic-genomic-range API and cohort filter optimization for expression assay data

April 29, 2025

Release for 29-Apr-2025

• Security patching of Docker containers

• Security patching of the NVIDIA drivers to address CVE-2025-23244 and related CVE-2025-23245 and CVE-2025-23246

• Efficiency enhancements on writable symlinks and drives

• Apollo: no release

April 15, 2025

Release for 15-Apr-2025

• Security patching of Docker containers

• Dependency updates. Fixes to writable symlinks and user interface fixes for table displays

• Apollo: infrastructure upgrades

April 8, 2025

Release for 08-Apr-2025

• Security patching for EC2 instances and Docker containers

• Efficiency enhancements to project storage limits for more frequent reporting

• Refactoring of open source libraries to address security vulnerabilities, patching of the secure browser used in TREs and fixes to the file describe functionality regarding symlinks

• Apollo: No Release.

April 1, 2025

Release for 01-Apr-2025

• Security patching for Docker containers

• Enhancements on watermarking in data dispensals

• Apollo updates include:

  • Structural Variant and Fusion support in Somatic Variant

  • Add Pearson correlation coefficient output to scatterplot API

  • Fix fusion post-processing in somatic-genomic-range API

  • Update field validation for locus-details API

  • Add support for partitioned expression datasets

March 25, 2025

Release for 25-Mar-2025

• Security patching for Docker containers

• Titan bug fixes and efficiency enhancements

• Apollo: No release. Downtime from 4-5pm UTC (9-10am PDT) for infrastructure upgrades

March 18, 2025

Release for 18-Mar-2025

• Security patching of Docker containers

• Titan: bug fixes

• Apollo: Upgrade of vizserver infrastructure

March 11, 2025

Release for 11-Mar-2025

• Security patching of Docker containers and EC2 instances

• Backend updates to enhance the UI, tuning of the infrastructure and clarification of error messages

• Apollo: minor tuning of the infrastructure

March 4, 2025

Release for 04-Mar-2025

• Security patching of Docker containers

• Titan: efficiency enhancements on project storage limit functionality and archiving functionality

• Titan: Bug fixes including SSO issues for isolated customers

• Apollo: Configuration and infrastructure component upgrades

February 25, 2025

Release for 25-Feb-2025

• Security patching of Docker containers

• UI enhancements of the tool selector

• Apollo: no release

February 11, 2025

Release for 11-Feb-2025

• Fixes to bugs in writable symlinks and hardlink resolutions

• Apps: Subread featureCounts v0.2.0

• Apollo: no release

February 4, 2025

Release for 04-Feb-2025

• Infrastructure updates of node.js, AuroraDB

• Apps: gatk4_mutect2_variant_caller_and_filter v2.0.2, picard_downsample to v1.2.0 and picard_normalize_fasta to v1.2.0

• Apollo: updates to error messages when > 512 MB for dx extract_* commands

January 28, 2025

Release for 28-Jan-2025

• Security patching for Docker containers

• Adding information to the API logs — more detail in the API call

• Internal metering to drive efficiency enhancements

• Bug fixes to the User Interface

• Apps: Update GLnexus to v1.0.5, snpeff_annotate, Subread featureCounts v0.2.0

• Apollo: Internal upgrades to Spark 3.5.2

January 14, 2025

Release for 14-Jan-2025

• Security patching of EC2 and Docker containers

• Data catalog launch with conversational search (limited audience)

• Apps: bowtie2_fastq_read_mapper upgraded to v2.1.0 and app-freebayes upgraded to v3.0.0

• Apollo: SQL query updates to "all", "any", and "not-any" filters in the Cohort Browser